Cristhian Stuani struck twice at Camp Nou as Girona battled to a deserved 2-2 draw away to Barcelona, who saw their perfect LaLiga record end after Clement Lenglet's first-half red card.
Lionel Messi gave Barca the lead in the 19th minute and the champions looked set to collect a fifth straight league win before Lenglet was dismissed on his first league appearance for Barca following a VAR review.
Stuani levelled with a fantastic finish before half-time and five minutes after the restart the striker was on target again to give Girona hope of recording a famous victory.
But Gerard Pique rose highest in the penalty area to head home and salvage a draw for Barcelona, who move back above rivals Real Madrid into top spot despite dropping their first points of 2018-19.
Girona created the first clear chance in the fifth minute but Bernardo Espinosa headed an Aday Benitez corner into the arms of Marc-Andre ter Stegen.
Bono brilliantly denied Messi at the end of a dazzling solo run but he could do nothing about the Barca captain's opener, a fantastic first-time finish from 14 yards out after Arturo Vidal's fine work.
Barca were reduced to 10 men when Lenglet saw red following a VAR review, the defender having caught Pere Pons with his elbow, and Girona quickly made their man advantage count.
Benitez raided down the right wing and fed Stuani, who turned away from Pique and makeshift partner Sergio Busquets to slot a neat finish past Ter Stegen.
And Stuani put Girona into a shock lead in the 51st minute, slamming home a rebound after Ter Stegen had saved well from Portu.
Messi clipped the crossbar with a 30-yard free-kick before Pique drew Barca level with a clever header that set up a thrilling finale during which Ernesto Valverde's men were unable to break Girona's resistance.
What does it mean: Squad rotation backfires
Valverde left Barca stars Samuel Umtiti, Ivan Rakitic and Philippe Coutinho on the bench and while he could not have predicted Lenglet would see red in the first half, the decision did not pay off. Barca have to manage their squad the same way as anyone, but the champions have given up their two-point lead atop the table with Madrid drawing level thanks to their narrow defeat of Espanyol on Saturday.
Stuani continues to shine
Uruguay international Stuani outscored stars including Gareth Bale and Antoine Griezmann in LaLiga last season with 21 strikes and he has started 2018-19 in a similar vein of form. The former Middlesbrough striker has already hit five goals this season, more than anyone else in the division, and he deserved to be on the winning team.
Lenglet shows immaturity on debut
Given a rare opportunity to shine with Umtiti rested, Lenglet is unlikely to get another chance any time soon after his first-half red card. Even with the benefit of replays it was hard to tell whether there was any real malicious intent in his block on Pons, but he gave the referee a decision to make by thrusting out his arm in an unnatural manner. After consulting VAR, Jesus Gil Manzano felt Lenglet's foul deserved a red card.
Key Opta stats:
- Barcelona defender Gerard Pique has scored in each of his 12 LaLiga seasons (24 goals for Barcelona and two for Real Zaragoza).
- Stuani is the first player to score a brace against both Real Madrid and Barcelona in LaLiga in a calendar year in the 21st century.
- Bono made nine saves against Barcelona, the highest total by a goalkeeper in a LaLiga game this season (level with Tomas Vaclik against Levante)
- Barcelona are unbeaten in their last 39 La Liga home games (W32 D7), their longest run at Camp Nou in the competition since their 40 unbeaten home games between October 1991 and November 1993.
A midweek round of LaLiga games sees Barcelona travel to Leganes on Wednesday and on the following day Girona host Real Betis.
|Manchester United v Juventus: Ronaldo out to end dismal scoring record against Mourinho|
|Injured Ribery to miss Bayern´s clash with AEK|
|Wilshere would have stayed at Arsenal under Wenger|
|Mahomes stars again as Chiefs crush Bengals|
|Bolt must accept ´much less´ to join Mariners, says A-League chief|
|Klopp compares Liverpool to dog without favourite toy|
|Young leads Hawks to first win, Thunder fall in Westbrook´s return|
|Spalletti hits out at physical Milan – I had three players asking to be replaced|
|Cowboys, Ravens lose after missed kicks in final seconds|
|Hernangomez secures Nuggets´ win over Warriors with last-second block|
|Hasler returns to Manly on three-year deal|
|Sarri: Chelsea fans must respect Mourinho|
|Ronaldo learnt from Scholes – Pjanic praises Juventus star|
|CA dismisses spot-fixing claims|
|WATCH: Will Ferrell leads chants with LAFC fans|
|MLS Review: Galaxy on track for play-offs as Timbers, DC clinch spots|
|Elliott secures win at Hollywood Casino 400|
|Thunder´s Westbrook makes season debut against Kings|
|Saints beat Ravens after Tucker misses extra point|
|Rondo, Paul and Ingram banned after Lakers-Rockets fight|
|Saints QB Brees reaches another historic milestone|
|Biglia: VAR should have checked Nainggolan tackle|
|Gattuso not blaming Donnarumma for derby defeat|
|Seventh in Mexico will secure Hamilton´s fifth world title|
|Rooney fires DC United into MLS play-offs|
|Alonso slams ´amateur´ F1 rivals after latest crash|
|Spalletti fears lengthy Nainggolan absence|
|To the Max! Verstappen destroyed shoe fending off Hamilton|
|Icardi delight after Donnarumma error gives him another derby winner for Inter|
|Guardiola: Versatility the key for Stones|
|Vettel frustrated as mistakes continue to hamper title challenge|
|ECB refutes spot-fixing claims against England players|
|I thought we would do better - Hamilton queries Mercedes strategy|
|Inter 1 AC Milan 0: Icardi settles derby with dramatic late winner|
|Hamilton denied title party as Raikkonen wins in Austin|
|Patriots RB Michel out against Bears with gruesome knee injury|
|Kohli hails Rohit partnership after comprehensive India victory|
|Silva downplays his role after Everton super subs seal victory|
|Injured Bairstow out of final white-ball matches in Sri Lanka|
|Pliskova feeling confident after impressive start in Singapore|
|Big-hitting Imrul rescues Bangladesh in opening ODI|
|Leinster suffer late defeat at Toulouse, Newcastle snatch dramatic victory|
|Chargers pip Titans to dramatic London win|
|Everton 2 Crystal Palace 0: Substitutes Calvert-Lewin and Tosun clip Eagles´ wings|
|Thunderstorms push Andalucia Valderrama Masters into reserve day|
|Edmund masters Monfils to claim maiden singles title|
|Kohli and Rohit fire India to comprehensive ODI win|
|Manchester United didn´t play - David Luiz blasts Mourinho tactics|
|Svitolina out to silence ´haters´ in Singapore|
|Emre Can facing surgery on thyroid problem|
|Tsitsipas claims maiden ATP crown in Stockholm|
|Mariners boss Mulvey knows nothing of Bolt contract offer|
|WATCH: Vinicius Junior scores free-kick - then sees red!|
|Gronkowski ruled out of Bears clash|
|Khachanov enjoys home comforts with comprehensive Kremlin Cup win|
|Isner wants Wimbledon tie-break rule named after him|
|Hummels lauds ´outstanding´ Lewandowski|
|Liverpool´s defensive improvement no accident – Gomez|
|Pliskova overpowers defending champion Wozniacki in Singapore|
|Marquez dislocates shoulder celebrating MotoGP title|
|Henry taking positives from opening Monaco defeat|
|A-League Review: Mariners held as Bolt considers move|
|Dominant Svitolina ends Kvitova hoodoo in Singapore|
|Pereira warns Juventus to expect ´pumped up´ Manchester United|
|D´Antoni backs NBA to ´sort out´ Lakers-Rockets brawl|
|Mixed feelings for champion Marquez after Dovizioso crash|
|Bolt offered contract by Central Coast Mariners|
|Anthony accuses Rondo of spitting after Lakers-Rockets brawl|
|Martial insists he has good relationship with Mourinho|
|Bautista to replace Lorenzo at Phillip Island|