Israel Folau has been named on the wing as David Pocock is also set to make his return in Australia's Rugby Championship clash against Argentina.
Pocock (neck) and Folau (ankle) were included to make their returns from injury during Saturday's Test on the Gold Coast.
However, Folau has surprisingly been named on the right wing, meaning Dane Haylett-Petty retains his spot at full-back.
Folau has started his past 61 Tests at full-back, a run stretching back to 2013.
#BREAKING l Your #Wallabies team to face @lospumas in the FINAL home Test of the year this Sat Sept 15.— Qantas Wallabies (@qantaswallabies) September 13, 2018
TICKETS: https://t.co/lJcS2Ksx1e#TRC18 #AUSvARG #GoldBlooded pic.twitter.com/D6AKq9Aw27
The switch is just the latest shock selection by coach Michael Cheika, who dropped playmaker Bernard Foley to the bench a week ago.
That decision seemingly paid off as the Wallabies overcame South Africa 23-18 last time out.
Prop Sekope Kepu was named among the reserves for the clash against Argentina and is in line to earn his 97th Test cap.
Australia are bottom of the Rugby Championship table with one win from three – a record matched by Argentina.
Australia: Dane Haylett-Petty, Israel Folau, Reece Hodge, Matt Toomua, Marika Koroibete, Kurtley Beale, Will Genia; Scott Sio, Tatafu Polota-Nau, Allan Alaalatoa, Rory Arnold, Izack Rodda, Lukhan Tui, Michael Hooper, David Pocock.
Replacements: Folau Faingaa, Sekope Kepu, Taniela Tupou, Adam Coleman, Pete Samu, Nick Phipps, Bernard Foley, Jack Maddocks.
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