Radja Nainggolan will be out for "a while" after the midfielder was injured in Inter's derby victory against AC Milan, said Luciano Spalletti.
Nainggolan limped off after half an hour of Sunday's Serie A clash at San Siro, where Inter won 1-0 thanks to a late Mauro Icardi header.
The former Roma star appeared to sustain the injury in a heavy tackle from Lucas Biglia that saw the Milan midfielder booked, although Nainggolan also caught the Argentina international in the incident.
Nainggolan initially played on but after he was on the end of another firm challenge he was replaced by Borja Valero.
And Spalletti suggested Nainggolan could face a lengthy lay-off, with Inter next in action against Barcelona in the Champions League on Wednesday.
"Nainggolan has been chopped down," Spalletti said to Sky Sport Italia.
"We have to take him to the hospital and see. He won't be with us for a while."
|￣￣￣￣￣￣￣￣￣￣￣|— Inter (@Inter_en) October 21, 2018
\ (•◡•) /
| | pic.twitter.com/HQv85J7IYw
Both teams had a goal ruled out for offside while Stefan de Vrij hit the post in the first half, but Spalletti was in no doubt the result was fair.
"It's obvious Inter deserved it, we played from start to finish in their half, pressed high and went for it," the coach added.
"Therefore, we deserve compliments. Not because we wanted it more, but because we played better. If you say to me, 'The team that wanted it more got the win', that is not accurate. The team that played better football won the game.
"I came here to win, not to just sit on a bench for a season and bring home a salary. I came here to organise the future of Inter and the players must do the same.
"I liked that after the final whistle, Icardi said we must find consistency and keep pushing. Inter chose us to bring this side back to the level that the fans deserve. It is our job, we must do it with a sense of belonging and prove they were right to choose us.
"It's dangerous when you press high, as there is always the risk of conceding a counter, but we were perfect and forced Milan to continually lose the ball. We ensured Milan were incapable of playing their quality passing game that Gennaro Gattuso had spoken about."
|Molinari wins Race to Dubai|
|Rooney: Some ex-players can´t come to terms with England doing well|
|In a spin: England´s win against Sri Lanka sets new record|
|Ogier wins sixth straight WRC title|
|Rogic, Kruse to miss Socceroos´ Lebanon friendly|
|Joerger has Kings´ ´full support´, says GM Divac|
|England seal series win over Sri Lanka|
|Butler´s heroics spoil Walker´s 60-point game as 76ers beat Hornets|
|He´s an honest guy – Djokovic defends Zverev after Finals controversy|
|Bonucci boos a ´mistake´ by fans, says Mancinima|
|Ronaldo still part of Portugal squad – Santos|
|Santos satisfied as Portugal reach Nations League Finals|
|Howell holds onto RSM Classic lead|
|McLeish optimistic as Scotland zero in on Nations League promotion|
|Luis Enrique rejects criticism of Spain star De Gea|
|Schmidt dismisses Hansen´s Ireland World Cup favourites claim as ´banter´|
|There are always imbeciles – Bonucci hits back at fans after frosty San Siro reception|
|Portugal draw ´a step forward´ despite poor finishing – Mancini|
|Ireland were just too good - Read|
|Thomas at the double as France end losing streak|
|Albania 0 Scotland 4: Forrest double sets up promotion showdown|
|Italy 0 Portugal 0: European champions outplayed but secure Finals spot|
|Sensational Djokovic marches into final|
|Stander lauds Ireland´s ´unreal´ defence as All Blacks are thwarted|
|Dazzling Ireland claim historic All Blacks scalp in Dublin|
|Federer unimpressed with Zverev boos|
|Let´s get it on! Cheika relishing England clash|
|Croatia coach Dalic to speak with Lovren over Ramos remarks|
|Xhaka puts improved form down to ´freak´ Emery|
|De Gea not lacking confidence, says Spain´s Saul|
|Jordan goalkeeper scores from own penalty area in friendly against India|
|Pollard leads Springboks to Murrayfield victory|
|Fired-up Japan taught England a great lesson - Jones|
|Sarries leave it late to down Sale, Bath and Saints win|
|O´Shea fumes at disallowed Italy try|
|Southgate welcomes England selection quandary|
|Reaching Rooney´s England goals record ´definitely possible´ – Kane|
|Debut try for Cokanasiga as England rally to avoid Japan upset|
|Wembley will galvanise ´tired´ Croatia, insists Dalic|
|Zverev apologises for tie-break controversy amid O2 Arena heckles|
|Marquez happy with fifth after damaging shoulder in Valencia|
|Wales crush Tonga in Cardiff|
|Germany should keep faith in old guard - Bierhoff|
|Injured Lukaku to miss Belgium´s Nations League decider|
|Zverev knocks out Federer to reach maiden ATP Finals showpiece|
|Koroibete double maintains Australia´s 100 per cent record against Italy|
|Juventus´ Khedira sprains ankle in training|
|Van Dijk: Ramos is not my type of defender|
|Vinales grabs Valencia pole as Marquez crashes|
|I don´t deserve Ballon d´Or, Mbappe does – Hazard|
|Reed and Willett share lead in Dubai|
|Romagnoli joins long AC Milan injury list|
|Williamson steadies Black Caps after Boult heroics|
|Griezmann targets swift French response against Uruguay|
|Havertz´s future lies with Bayer Leverkusen – sporting director Boldt|
|Socceroos boss Arnold excited for future|
|South Africa triumph on Gold Coast in truncated T20 clash|
|Germany without Draxler for Netherlands game|
|Barcelona confirm Rakitic hamstring injury|
|Rain halts England´s post-tea flourish|
|Australia 1 South Korea 1: Luongo seals late draw for Socceroos|
|Irving thrives on ´peace´ of being in the zone|
|Lloris admits France could have lost by more|
|Dybala impressed by Argentina´s improved spirit|
|Arsenal chief confirms Super League talks|
|Hooker knocks out Saucedo to retain WBO strap|
|NBA wrap: Kyrie Irving sizzles as Celtics beat Raptors in overtime|
|Jimmy Butler aims dig at Timberwolves following 76ers home debut|
|Koeman surprised by dominant Netherlands|
|Southgate rallies England ahead of Nations League decider|