Hugo Lloris is a doubt for Tottenham's trip to Southampton on Sunday, but Mauricio Pochettino confirmed centre-back Toby Alderweireld is on the comeback trail.
Belgium international Alderweireld has not played since November 1 as a result of a hamstring injury sustained against Real Madrid in the Champions League.
The centre-back is nearly ready to rejoin Spurs' training sessions but will not be available to face former club Southampton, while Lloris is struggling due to illness.
"I don't know [if Lloris will be fit]," Pochettino told reporters on Friday. "Difficult to say.
"We need to wait today and tomorrow and then assess him tomorrow and if he's available or not. I think it's a flu or a virus. It's between this.
"I think everyone, with this weather, apart from today's fantastic weather, has struggled a little bit. It's an epidemic across Europe, not just here in the UK."
TEAM NEWS: Hugo Lloris (illness) is being monitored to assess his availability for Sunday's game against Southampton. pic.twitter.com/6EemPVStUW— Tottenham Hotspur (@SpursOfficial) January 19, 2018
While Michel Vorm may have to deputise for the France goalkeeper on Sunday, long-term absentee Alderweireld is closing in on a return to first-team action.
"Maybe today if all is OK with him then tomorrow he can integrate himself in some exercise with the group and a little bit step by step build his fitness to be available again," Pochettino said. "Tomorrow, but if all is OK with a scan today.
"I am very pleased when the players that are injured are in their preparation to return like Harry Winks or in this case, Toby or Danny Rose. I think every manager wants all their players fit and available to select.
"That is the most important thing. We have a very busy period ahead and we need all the team fit and available to play."
Tottenham traditionally do not do much business in the mid-season transfer window, with Lewis Holtby and DeAndre Yedlin two of the only January arrivals in recent years.
And Pochettino is not expecting things to change in 2018, although his side are three points adrift of Champions League qualification ahead of the Argentinian's return to St Mary's.
"To be honest, it's difficult but in some point you always dream," said Pochettino, who denied reports Chelsea have made a bid for striker Fernando Llorente. "But not too much exciting. If it happens, it happens, if not happen, then not happen. We're happy with the squad.
"I am not a specialist in the market. I think I am a specialist in football and sometimes not too much. The market is the market and it's difficult to assess. For the specialists, it is difficult to predict what is happening and what is going on.
"People that think one year or ago or six months ago something wouldn't happen and now it is happening. The most important thing is to be happy with everything that is moving around you. But I am not a specialist in the market and I cannot tell what is going on."
|Huget to make first France appearance in a year|
|Mourinho and squad ´united´ despite ´mixed´ start, says Woodward|
|Petaia and Gordon to make Wallabies debuts in Padova|
|Barcelona star Arthur determined not to let Xavi praise go to his head|
|Youthful Netherlands have forged strong bond - Wijnaldum|
|Premier League confirms £5m package for departing chief Scudamore|
|Thiem blasts past Nishikori to keep semi-final hopes alive|
|He´s always got time for me – Gerrard loved learning from Liverpool boss Klopp|
|Kearney and Ringrose return for All Blacks clash|
|Molinari on course for Race to Dubai title, Smith and Otaegui lead|
|Premier League to implement VAR from 2019-20 season|
|FSF urges Premier League clubs to reject Scudamore ´golden handshake´ request|
|Rhinos pull off Merrin coup|
|Ribery apologises for reporter altercation|
|Ford to captain much-changed England, Cokanasiga starts|
|Crotty replaces injured Williams for Ireland showdown|
|Classy Roshen gives Sri Lanka unlikely lead|
|Injured Lukaku out of Belgium-Iceland Nations League clash|
|Rooney ´passionate´ about future coaching career|
|Mehidy spins Tigers to victory despite second Taylor hundred|
|Rooney deserves special England day - Antonio|
|LeBron thinks back to his roots after latest milestone|
|Messi to return for Argentina next year - General manager Burruchaga|
|Walton salutes LeBron after he surpasses Chamberlain|
|Croatia´s Dalic and Modric not out for Spain revenge|
|Rondo to miss ´a few weeks´ with broken hand|
|Gabi, Juanfran hopeful over Oblak´s Atletico future|
|England rookie Wilson not comparing himself to Kane|
|WATCH: The baskets that moved LeBron James up the all-time NBA scoring list|
|LeBron moves into fifth on scoring list, 76ers fall in Butler´s debut|
|LeBron James into top five NBA scorers: Five quotes from league legends on his greatness|
|LeBron passes Chamberlain for fifth on all-time scoring list|
|Butler: 76ers need time to gel|
|South Africa lose 28-9 in Windies defeat|
|Delph impressed by ´special´ Sancho|
|Bolt may give up on football career despite ´a lot of offers´|
|We´re better than Dortmund – Wagner urges Bayern to respond|
|Raptors fans give former coach Casey standing ovation in return|
|Martinez hails Hazard leadership|
|Muller going through ´difficult´ period, says Low|
|Betances wants Yankees to sign Machado|
|Rays´ Snell, Mets´ deGrom win Cy Young Awards|
|Dinwiddie to debut Stan Lee-inspired shoes against Heat|
|Iberostar Tenerife and Segafredo Virtus Bologna stay perfect in BCL|
|Rooney wanted to finish career at Manchester United|
|Red Sox give manager Cora contract extension through at least 2021|
|WATCH: Ronnie O´Sullivan hits blue with calamitous break-off shot|
|Matuidi: Mbappe has a great personality, like Ronaldo, Messi and Zlatan|
|Cilic beats Isner to hand Djokovic semi-final spot|
|Mendy undergoes knee surgery|
|Warriors´ Curry will not play during three-game road trip|
|Ramos refuses to retaliate after Lovren jibe|
|Qatar pull off shock win over Switzerland|
|Tuilagi could make England return against Australia|
|Rooney has earned England reward - Sarachan|
|Croatia thrashing means nothing now – Luis Enrique|
|Chelsea and Everton among Arnautovic suitors, claims agent|
|TJ Watt hopes to win NFL sacks race with brother JJ|
|Modric defends Ramos after Lovren comments|
|Southgate hails ´outstanding´ Delph as he talks up England strength in depth|
|No war with Manchester United over Fellaini, insists Martinez|
|Rooney to wear number 10 shirt against USA and receive armband from Delph|
|I don´t feel pressure of Liverpool expectations, claims Klopp|
|Steelers´ Roethlisberger texted Bell but ´didn’t hear back´|
|Reus and Kroos to sit out Germany´s clash with Russia|
|Van Dijk happy to recommend De Ligt if Liverpool ask|
|Sauber announce launch of junior programme|
|No ´breathtaking tennis´ in Djokovic´s win against Zverev|
|Curran: England spinners will be key in Kandy|
|Djokovic charges past Zverev to move closer to ATP Finals progression|