Estudiantes reached the Copa Libertadores last 16 with a dramatic win over Nacional, while Independiente also moved into the knockout stage.
A pair of penalties from Juan Ferney Otero saw Estudiantes overcome Nacional 3-1 in La Plata Thursday.
Nacional – only needing a draw to progress from Group 6 – took an early lead through Matias Zunino, who scrambled in from a corner.
But the final half-hour belonged to Estudiantes, who dramatically struck three times to advance.
Otero equalised from the penalty spot after a handball in the area before Lucas Melano finished clinically to make it 2-1.
Nacional had Gonzalo Bergessio sent off in the 75th minute, while the hosts were also reduced to 10 men when Rodrigo Brana saw red.
Needing another goal to advance on goal difference, Estudiantes were awarded a controversial late penalty.
Otero again stepped up, converting the 90th-minute spot-kick to seal an incredible comeback win before the visitors finished with nine men when Christian Oliva saw red.
Santos finished top of the group and drew 0-0 at home to Real Garcilaso in their final outing.
Independiente progressed after a 2-0 victory over Deportivo Lara, while Group 7 winners Corinthians lost 1-0 to Millonarios.
Atletico Nacional and Colo-Colo moved through from Group 2 after their 0-0 draw.
Delfin needed a win at Bolivar to move into second, but they were beaten 2-1 as Juanmi Callejon scored a brace.
|´Positive´ Pogba not bitter towards media, says Varane|
|Portugal privileged to have ´humble´ Ronaldo, says Pepe|
|Strickland breaks hand punching door after blown save, out for up to eight weeks|
|He will have received good money – Costa delighted by Griezmann extension|
|Kane: Pochettino sent me love hearts after World Cup heroics|
|Nationals place Adams on 10-day DL with broken finger|
|Dybala: I can play alongside Messi|
|Lewandowski: Poland didn´t take enough risks|
|England´s Kane aiming to reach Ronaldo, Messi levels with World Cup performances|
|Kicker given three-year match-fixing ban|
|England confirm Alli thigh injury|
|Federer through, Zverev out in Halle|
|Back on the map and earning letters from ladies, Tabarez embraces Uruguay´s heritage|
|Rampant England rout Australia in record-breaking display|
|Pulisic in right place at Dortmund, says Arena|
|Wilshere confirms Arsenal exit|
|NASCAR at Sonoma: TV schedule, standings, qualifying drivers for Toyota/Save Mart 350|
|Muguruza and Kvitova cruise through in Birmingham|
|Leno among top 10 most expensive goalkeepers|
|Pained Salah unable to halt Russia´s unlikely march|
|Kyrgios downs ´legend´ Murray as Dimitrov and Djokovic progress|
|Neymar pain normal – Coutinho unconcerned by ankle issue|
|Russia 3 Egypt 1: Salah strikes but hosts right on course for last 16|
|We must make Ronaldo less exceptional, says Morocco boss Renard|
|Chandimal handed one-Test ball tampering ban, faces further ICC charge|
|Arsenal sign goalkeeper Leno from Leverkusen|
|Mexico style in Germany win surprised Arena|
|Monaco complete €20m move for Lyon teenager Geubbels|
|Saudi team don´t know cause of aeroplane fire, Pizzi reveals|
|Champions League qualifying draw: Celtic travel to Armenia, Ajax face Sturm Graz|
|I´ve never seen a player win on his own – Santos shrugs off Ronaldo dependence|
|Murray impresses despite narrow defeat on return|
|West Ham land club-record Diop signing|
|El Hadji Diouf hails ´perfect start´ for Senegal|
|Cisse and Senegal give cause for African celebration|
|Carvajal ready to face Iran - Hierro|
|Japan´s World Cup victory over Colombia sparks celebrations on the streets of Tokyo|
|Poland 1 Senegal 2: Good fortune and bad errors hand Africans Group H win|
|England shatter ODI world record with total of 481 against Australia|
|Best yet to come from England hero Kane, says Rashford|
|Salah starts for Egypt against Russia|
|De Jong expects to stay at Ajax|
|Barcelona angered by Pique´s involvement in Griezmann saga|
|Federer begins Halle defence with comfortable Bedene win|
|Tabarez not worried by slow Suarez start|
|Brazil´s Neymar felt pain in his ankle, CBF confirms|
|Griezmann understands Atletico fans´ nerves over Barcelona speculation|
|Queiroz salutes Hierro for uniting Spain|
|Stump from Scotland´s defeat of England auctioned for charity|
|Red Bull will not have works team label, confirm Honda|
|Neymar hobbles out of Brazil World Cup training|
|Ronaldo´s revelry, Messi´s miss and Sanchez´s shocker - Russia 2018, World Cup of the penalty|
|Brazil ask FIFA to explain VAR decisions against Switzerland|
|Colombia 1 Japan 2: Sanchez red spoils Pekerman´s plans|
|Argentina v Croatia: Mercado wants an end to ´Messidependencia´|
|Hoffenheim director suggests €50m bid could land Kramaric|
|England will emerge as a ´champion team´, insists Jones|
|Ryder Cup teams shaping up great, says Strange|
|We cannot replace Iniesta – Abidal|
|Colombia´s Sanchez sees second-quickest World Cup red card|
|France v Peru: Varane and Les Bleus calm after unconvincing start|
|Semenya challenges IAAF hyperandrogenism rule with CAS|
|No Germany line-up changes needed, says Neuer|
|James absent from Colombia line-up|
|Alli to have scan on thigh knock after England win|
|Mooy not using World Cup to facilitate transfer from Huddersfield|
|Billy Vunipola a big loss for England, says Vermeulen|
|´Incredible´ Firmino works like a defender, says Mane|
|Jackson and Olding could make Ireland returns|
|Stokes and Woakes ruled out of T20I matches|